The paths of implementing the construction of counties with strong agriculture were explored based on the county-level major functional zones to promote the rural revitalization comprehensively. The main battlefield for constructing a nation with strong agriculture is the construction of counties with strong agriculture with considering factors including the characteristics， differences， and development levels of regions in China. This article clarified the connotation and characteristics of counties with strong agriculture under the strategy of accelerating the construction of China as a nation with strong agriculture from the perspective of county-level major functional zones. A frame of reference for constructing counties with strong agriculture in major areas of agricultural production in China was provided through the international comparison. A reference path for constructing counties with strong agriculture in typical zones of ecological function was provided through the empirical analyses in China. A comprehensive index measurement model for the degree of achievement of counties with strong agriculture was established， which can select different core indexes based on the State designated functional zones mandates to measure the level of achievement of strong counties with strong agriculture. The key strategies and priorities for promoting the construction of a county with strong agriculture were discussed based on the analyses to provide basic support for scientifically guiding the construction of a county with strong agriculture and accelerating the realization of China as a nation with strong agriculture.