To obtain more measures to controlthe clubroot disease of Chinese cabbage, Bacillus subtilis XF1 lysis solution of Lentinus edodes mycelia (EXF1) and its acetone extract were used as biological resistance inducers (BRI) and their effects on controlling clubroot disease and on microbial population in Chinease cabbage rhizoshere were tested based on the pot culture experiment. The results showed that EXF-1 and its acetone extract could control 65.07% and 42.20% of the clubroot disease, respectively. BRIs increased the numbers of Bacillus and fungi, but reduced that of actinomycetes. Based on the results of 120 h culture in Biolog Eco-Plates, sugars and amino acids could explain 35.0% and 10.7% of the variance among 31 principal factors. Therefore, BRI could control the clubroot disease and affect the microbial populations in the soil.