The observation data of 18 national meteorological stations in western Hubei Province were used to conduct risk index analysis of tobacco high impact meteorological disasters in recent 60 years based on the established risk index system of damages caused by drought, chilling, steady rain, rainstorm, high temperature and high heat, and make comparison between the previous and the last 30 years to identify the effects of climate changes on tobacco meteorological disaster risk in western Hubei. The results showed that the risk of drought, steady rain and rainstorm in tobacco growing areas in western Hubei Province reduced overall in the past 30 years in term of time dimension. But the risk of drought in southwestern Hubei Province increased, indicating that water condition had gradually become one of the main factors affecting local tobacco production. Under the background of climate warming, the risk of chilling and high temperature and heat damage had shown a trend of partial mitigation and general aggravation. Regionally, Zaoyang, Nanzhang and other places were continuously affected by drought. The chilling damage was concentrated in high altitude areas, while high temperature and heat damage was distributed in river valleys. Wufeng and Xingshan were relatively high incidence centers of hail and gale, so it was necessary to prevent the damage brought by severe convective weather. It could be seen that the main meteorological disasters and climate changes affecting tobacco production in western Hubei Province were different due to different geographical locations. From the distribution of comprehensive meteorological disaster risk, except the northeastern Badong and the northern part of Jianshi, the comprehensive risk level of meteorological disasters in most areas of Enshi in last 30 years was still “medium” or above, with Hefeng being the most serious.