To investigate the effect of plant secondary metabolites on the yield increase of different crops，the metabolites of sugar beet and sugarcane were extracted and separated，optimized in proportion，and then chelated with humic acid to form a product according to the national standard of water-soluble fertilizers containing humic acid.Field and hydroponic experiments were conducted to study the yield increase effect and mechanism of this product on 15 crops such as wheat.Two treatments were set up in the experiment：（1） conventional fertilization； （2） conventional fertilization + plant-derived secondary metabolites products，which were applied by foliar spraying，fertilizer mixing，and root irrigation according to different crop types.The results showed that compared with the control，the yield of 15 crops were increased by 5.2% to 21.1% by applying plant-derived secondary metabolites.The germination potential of rice，corn，and cotton seeds increased by 6.6%，11.5%，and 15.2%，respectively，and the germination rate increased by 2.6%，3.5%，and 6.1%，respectively.The total root length，total surface area，and root tip number of wheat roots increased by 54.44%，60.57%，and 30.43%，respectively.The SPAD values of potato，Chinese cabbage，cabbage，and wheat leaves increased by 4.8%，8.7%，6.6%，and 9.7%，respectively.The net photosynthetic rate of wheat leaves increased by 7.9%，and the Vc content of potatoes，Chinese cabbage，and chili increased by 40.8%，22.9%，and 28.51%，respectively.However，the nitrate content decreased by 28.8%，23.9%，and 20.27%，respectively.The sugar content of grapes and beets increased by 21.81% and 15.75%，respectively.The above results indicate that plant secondary metabolites could increase the yield and improve the quality of crop by enhancing the root vitality，promoting nutrient absorption，increasing chlorophyll content，and promoting the accumulation of photosynthetic products，and have good effects of improving fertilizer quality and efficiency.